Does Hyaluronic Acid Cause Acne?


Published: 23 Mar 2025


Breakouts are frustrating enough without skincare making them worse. If you’ve just added a new product and are suddenly seeing pimples, you might be asking: Does hyaluronic acid cause acne?

Don’t worry, this guide will walk you through the real reasons behind breakouts and how to protect your skin while staying moisturized.

1- Can Hyaluronic Acid Cause Acne?

No, hyaluronic acid does not directly cause acne. It is a hydrating ingredient that helps maintain skin moisture without clogging pores. (1)

However, some people experience breakouts after using HA products. Why? Let’s break it down.

1.1 Why Do Some People Break Out After Using Hyaluronic Acid?

1.1.1 Low-Quality Products

  • Some HA serums or creams contain comedogenic (pore-clogging) ingredients like oils, silicones, or heavy emollients that can trigger breakouts.

1.1.2 Incorrect Application

  • Applying HA on dry skin can actually pull moisture from deeper layers of your skin, leading to dryness and irritation, which might result in breakouts. It works best when applied on damp skin, followed by a moisturizer.
Young white male having redness on his face showing allergic reaction

1.1.3 Reaction to Added Ingredients

  • Many HA products contain fragrances, preservatives, or silicones that can irritate sensitive or acne-prone skin. Always check the ingredient list before buying.

Wondering if your product is to blame? Keep reading. The next part will show you how to pick the right hyaluronic acid.

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2- How to Use Hyaluronic Acid Without Causing Breakouts

Using hyaluronic acid the wrong way can lead to dryness, irritation, or even breakouts—but when used correctly, it can be a game-changer for your skin.

Here’s how to make the most of it without clogging pores or worsening acne.

2.1 Choose the Right Product

  • Pick a pure, water-based, and fragrance-free HA serum.
  • Avoid HA products that contain oils, alcohol, or heavy occlusive ingredients (like petrolatum or coconut oil), as they may trigger breakouts.

2.2 Apply It the Right Way

  • Always apply on damp skin to lock in moisture. If applied on dry skin, HA can actually pull moisture out, making your skin dehydrated.

  • Follow up with a lightweight, non-comedogenic moisturizer to seal in hydration.

2.3 Patch Test Before Full Use

  • Test the product on a small area of your skin before applying it all over your face. This helps prevent unexpected reactions.
Young white girl has applied a cream on both sides of her face-only on a limited-surface

2.4 Pair It Wisely with Other Products

  • Avoid layering HA with comedogenic creams or strong acne treatments at the same time.
  • If you’re using actives like retinoids or salicylic acid, apply HA after them to soothe potential irritation.

3- Hyaluronic Acid and Acne-Prone Skin: Benefits and Misconceptions

Hyaluronic acid is often misunderstood in the acne community. Some fear it might worsen breakouts, while others think of its hydrating and soothing properties. Let’s clear up the confusion.

White young girl is smiling while applying the medicine on her face with sucker

3.1 Benefits of Hyaluronic Acid for Acne-Prone Skin

  • Keeps Skin Hydrated Without Causing Oiliness
    • Acne-prone skin is often dehydrated, especially if you use strong acne treatments. HA attracts moisture without making your skin greasy.
  • Strengthens the Skin Barrier and Reduces Inflammation
    • A weak skin barrier makes acne worse. HA helps repair and protect the barrier, reducing redness and irritation.
  • Works Well with Acne Treatments
    • Strong acne treatments like benzoyl peroxide, retinoids, and salicylic acid can cause dryness and peeling. HA helps counteract this without interfering with treatment effectiveness.

4- Real-Life Stories and Experiences

Many skincare lovers on Reddit shared surprising experiences that raise the same question: Does hyaluronic acid cause acne? One user had combination skin and loved experimenting with new products.

After adding hyaluronic acid serums from The Ordinary and Makeup Revolution to their routine, they noticed a sudden breakout along their jawline that hadn’t happened in nearly a year. They wondered if hyaluronic acid could be the reason.

Others agreed:

  • “TO hyaluronic surely broke me out!” said one user with dry, acne-prone skin. Their acne cleared up soon after they stopped using the HA serum.

  • Another user shared, “I thought I was crazy because everyone says HA is the best. I stopped using it, and now my skin is calming down.”

  • Some pointed out that maybe it’s not the hyaluronic acid itself but other ingredients (like pentylene glycol) in the formula that triggered the breakouts.

At the same time, a few users felt HA shouldn’t cause acne because it’s usually non-comedogenic (meaning it shouldn’t clog pores).

While hyaluronic acid is praised for hydration, for some people, it might be a hidden trigger for breakouts, either because of the product’s formulation or how their skin personally reacts.

Curious to learn more? Check out our next article on

4- Conclusion

So, guys, in this article, we’ve covered the question Does Hyaluronic Acid Cause Acne? in detail. To sum it up, HA itself doesn’t cause breakouts, but the wrong formulation or improper use might lead to issues.

My advice? Stick to a high-quality, non-comedogenic HA serum and always follow up with a moisturizer to seal in hydration. If you have acne-prone skin, avoid HA products with heavy oils or silicones.

Found this helpful? Share it with a friend who’s scared of trying HA

5- FAQs

Can hyaluronic acid make acne worse?

No, hyaluronic acid itself doesn’t cause acne. However, if your HA product contains comedogenic ingredients or is used incorrectly (like on dry skin without a moisturizer), it may lead to breakouts. Always check the ingredient list and apply HA on damp skin for best results.

Is hyaluronic acid safe for oily, acne-prone skin?

Yes! HA is lightweight, non-greasy, and hydrates the skin without clogging pores. Just make sure to choose an oil-free, fragrance-free formula to avoid irritation.

Does hyaluronic acid clog pores?

No, pure hyaluronic acid is non-comedogenic, meaning it won’t clog pores. But some HA serums contain oils, silicones, or thickening agents that might be problematic for acne-prone skin. Always read the label before buying.

Can hyaluronic acid help pimples heal faster?

Yes, it can! HA keeps your skin hydrated, which helps speed up the healing process of acne marks and reduces dryness from acne treatments. But it won’t directly kill acne-causing bacteria.

Does hyaluronic acid cause purging?

No, HA does not cause purging because it doesn’t exfoliate the skin. Purging happens with active ingredients like retinoids or AHAs/BHAs. If you notice breakouts, it might be due to other ingredients in the product.

Should I use hyaluronic acid before or after moisturizer?

Apply HA before moisturising while your skin is still damp. This helps HA pull in moisture and keep your skin hydrated. Then, seal it in with a good non-comedogenic moisturizer.

Can I use hyaluronic acid with acne treatments like benzoyl peroxide or retinol?

Yes! HA is great to pair with acne treatments because it prevents excessive dryness and irritation. Just apply your acne treatment first, let it absorb, and then follow with HA and moisturizer.

Will hyaluronic acid help with blackheads?

Not directly, but it supports overall skin health by keeping it hydrated. If you struggle with blackheads, pair HA with exfoliating acids like salicylic acid for better results.

How do I know if hyaluronic acid is breaking me out?

If you notice breakouts after using a new HA product, check the ingredient list for oils, fragrances, or silicones. Try switching to a simple, pure HA serum and see if the breakouts stop. Always do a patch test before using any new product.

Can I use hyaluronic acid every day?

Yes! HA is gentle and safe for daily use, even twice a day. Just make sure to apply it on damp skin and follow with a moisturizer to prevent dehydration.

References

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📚 Sources

1- Behrangi E, Dehghani A, Sheikhzadeh F, Goodarzi A, Roohaninasab M. Evaluation and comparison of the efficacy and safety of cross-linked and non-cross-linked hyaluronic acid in combination with botulinum toxin type A in the treatment of atrophic acne scars: A double-blind randomized clinical trial. Skin Res Technol. 2024 Jan;30(1):e13541. doi: 10.1111/srt.13541. PMID: 38174839; PMCID: PMC10765352.
https://pubmed.ncbi.nlm.nih.gov/38174839/

2- Dierickx C, Larsson MK, Blomster S. Effectiveness and Safety of Acne Scar Treatment With Nonanimal Stabilized Hyaluronic Acid Gel. Dermatol Surg. 2018 Nov;44 Suppl 1:S10-S18. doi: 10.1097/DSS.0000000000001689. PMID: 30358630.
https://pubmed.ncbi.nlm.nih.gov/30358630/

3- Jung, Yu Ra, Hwang, Chul, Ha, Jeong-Min– Hyaluronic acid decreases lipid synthesis in sebaceous glands. SN – 0022-202X doi: 10.1016/j.jid.2017.01.017
https://doi.org/10.1016/j.jid.2017.01.017

4- Schlesinger, T., & Powell, C. R. (2012). Efficacy and Safety of a Low-Molecular Weight Hyaluronic Acid Topical Gel in the Treatment of Facial Seborrheic Dermatitis. The Journal of Clinical and Aesthetic Dermatology, 5(10), 20. https://pmc.ncbi.nlm.nih.gov/articles/PMC3486775/


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MedicaWire follows strict sourcing guidelines and only references peer-reviewed studies, academic institutions, and reputable medical associations. We update content regularly to reflect new health information.




Dr Jawwad Ahmad Avatar

Dr. Jawwad, MBBS Doctor & Medical WriterDr. Jawwad is an experienced medical writer specializing in health and wellness topics. With a strong background in clinical knowledge and SEO-focused writing, he is passionate about simplifying complex medical information for readers. His mission is to ensure that every article published on MedicaWire is accurate, trustworthy, and medically sound.


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